Intranasal Drug Delivery (Systemic)

ZTECH-L™ and ZTECH-P™ delivery systems are designed for non-invasive systemic delivery of drugs, biopharmaceuticals, biologics or botanicals via the nasal route. Intranasal delivery applications include pain management, migraine crisis, hormone replacement, seizures, anaphylaxis, emesis, anxiety & depression, hypoglycemia & diabetes, cannabinoids, proteins & peptides, vaccines, anti-virals and biomedical countermeasures.

ZTECH-L™ and ZTECH-P™ intranasal drug delivery systems employ a patient-centric design to facilitate self-administration, ease of use and consistent precise delivery. ZTECH-L™ nasal delivery systems are designed for aqueous or non-aqueous liquid formulations and can be configured to dispense a targeted dose ranging from 20 µL to 110 µL per dose.  ZTECH-P™ nasal delivery systems can be configured for powder delivery, or to auto-reconstitute a dry powder formulation to a liquid, or auto-combine two separately packaged liquid formulations at the time of dosing by the patient or caregiver.  ZTECH-L™ and ZTECH-P™ nasal delivery systems are available in mono-dose disposable, mono-dose cartridge reloadable and multi-dose dispenser configurations.

ZTECH-L™ OrionMRQ™ mono-dose nasal delivery system

ZTECH-L™ OrionMRQ™ mono-dose reloadable nasal delivery system

OrionMRQ with on-board 4 dose storage compartment

OrionMRQ unit dose reloadable nasal cartridge

The OrionMRQ is a mono-dose reloadable, precision metered dose nasal dispenser for liquid formulations.  The device provides on-board storage for up to 4 unit doses, can be easily reloaded by the patient or caregiver and is convenient to carry in a purse of pocket.

ZTECH-L™ OrionMRS™ mono-dose reloadable nasal delivery system (liquid)

The OrionMRS is a mono-dose, reloadable, precision metered dose nasal dispenser for liquid formulations.  The device is ultra-compact, can be easily reloaded by the patient or caregiver and is convenient to carry in a purse or pocket.

ZTECH-L™ OrionSDX™ mono-dose disposable nasal delivery system (liquid)

ZTECH-L™ OrionSDX™ is a single dose, disposable, precision metered dose nasal dispenser for liquid formulations.  The device is ultra-compact and is configured for immediate use by the patient, caregiver or first responder.  The ultra-compact size makes it easy to carry and enables space efficient storage for strategic stockpiling of large quantities of ready to use countermeasures.

ZTECH-P™ CygnusSDX™ nasal powder delivery system

The CygnusSDX is a single dose, disposable, precision metered dose nasal dispenser for powder formulations.  The device is ultra-compact and is configured for immediate emergency use by the patient, caregive or first responder.  The ultra-compact size makes it easy to carry and enable space efficient storage for strategic stockpiling of large quantities of ready to use countermeasures.

Key performance features of our ZTECH-L™ and ZTECH-P™ intranasal drug delivery systems include:

  • Liquid, powder, reconstituted powder to liquid dispenser configurations
  • Mono-dose disposable and mono-dose reloadable configurations available
  • Intuitive design and operation to facilitate first use
  • Compact dispenser footprint for ease of carry in a purse or pocket
  • Side actuation dispenser device for ease of use
  • No device priming required
  • Mechanically actuated dispense eliminates the need for battery power
  • Safety lock to prevent inadvertent dispense during handling, storage or transport
  • Intuitive dispenser operation facilitates first time use
  • Dose counter
  • Orientation independent device actuation
  • Configurable spray plume
  • Metal free fluid delivery path
  • Non-sterile and aseptic packaging for preservative free formulations
  • Sterility assurance throughout the “in use” product life and in the dispensed dose
  • Exceptional primary container barrier properties for shelf stability
  • Tamper resistant packaging
  • Commercially scalable, cost efficient design for manufacturing

Key performance features of our ZTECH-L™ and ZTECH-P™ intranasal drug delivery systems include:

  • Liquid, powder, reconstituted powder to liquid dispenser configurations
  • Mono-dose disposable and mono-dose reloadable configurations available
  • Intuitive design and operation to facilitate first use
  • Compact dispenser footprint for ease of carry in a purse or pocket
  • Side actuation dispenser device for ease of use
  • No device priming required
  • Mechanically actuated dispense eliminates the need for battery power

  • Safety lock to prevent inadvertent dispense during handling, storage or transport

  • Intuitive dispenser operation facilitates first time use

  • Dose counter
  • Orientation independent device actuation
  • Configurable spray plume
  • Metal free fluid delivery path
  • Non-sterile and aseptic packaging for preservative free formulations
  • Sterility assurance throughout the “in use” product life and in the dispensed dose
  • Exceptional primary container barrier properties for shelf stability
  • Tamper resistant packaging
  • Commercially scalable, cost efficient design for manufacturing

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