Ophthalmic Drug Delivery Systems

ZEOx1™ and ZEOx2™ ophthalmic drug delivery systems are designed for dispensing drug, biopharmaceutical, biologic and botanical theraputics for treating glaucoma, macular degeneration, presbyopia, allergy, dry eye, anti-viral, anti-infective and anti-inflammatory indications.  Our delivery systems employ a patient-centric design to facilitate self-administration, ease of use and compliance. Our ergonomic design simplifies patient usage, reducing administration errors and waste typically found with traditional eye drop delivery devices. These unique capabilities provide superior cost economics for patients, third party payors and drug manufacturers.

ZEOx1™ delivery systems can be configured for aqueous and non-aqueous liquid formulations spanning a broad range of fluidic properties.  ZEOx2™ ophthalmic delivery systems can be configured to auto-reconstitute a dry powder formulation to a liquid, or auto-combine two separately packaged liquid formulations at the time of dosing by the patient or caregiver.

AquilaMD™ Multi-Dose Ophthalmic Delivery System

AquilaMD™ ultra compact multi-dose ophthalmic delivery system

AquilaMD™ optional use folding eye guide

AquilaMD™ patient reloadable dose clip

The AquilaMD multi-dose ophthalmic delivery system utilizes a reloadable ten (10) dose clip for precision dosing of preservative free ophthalmic drug formulations. The AquilaMD operates in any physical orientation and can be calibrated to dispense a precise dose ranging from 5 µL to 26 µL. The AquilaMD’s ultra compact “credit card” size design makes it easy to carry in a purse or a pocket. An optional use folding eyeguide aids in proper positioning of the dispenser to ensure accurate delivery to the eye.  Each dose is individually packaged with a single use dispensing channel to maintain sterility of every delivered dose. An easy to read dose counter informs the patient when it is time to replace the clip which is a simple process of sliding open the top of the dispenser, discarding the spent clip and dropping in a new clip. Operating the AquilaMD dispenser is a simple three step process,  index the device, position the device to the eye and press the dispense button – no priming is required. Safety features prevent the device from inadvertent dispense.

The AquilaMD multi-dose ophthalmic delivery system utilizes a reloadable ten (10) dose clip for precision dosing of preservative free ophthalmic drug formulations. The AquilaMD operates in any physical orientation and can be calibrated to dispense a precise dose ranging from 5 µL to 26 µL. The AquilaMD’s ultra compact “credit card” size design makes it easy to carry in a purse or a pocket. An optional use folding eyeguide aids in proper positioning of the dispenser to ensure accurate delivery to the eye.  Each dose is individually packaged with a single use dispensing channel to maintain sterility of every delivered dose. An easy to read dose counter informs the patient when it is time to replace the clip which is a simple process of sliding open the top of the dispenser, discarding the spent clip and dropping in a new clip. Operating the AquilaMD dispenser is a simple three step process,  index the device, position the device to the eye and press the dispense button – no priming is required. Safety features prevent the device from inadvertent dispense.

AriesMD™ Multi-Dose Ophthalmic Delivery System

AriesMD™ ophthalmic multi-dose cartridge reloadable device

AriesMD™ multi-dose cartridge

AriesMD™ ophthalmic multi-dose cartridge reloadable device

The AriesMD multi-dose ophthalmic delivery system utilizes a reloadable, twenty (20) dose disc cartridge for precision dosing of preservative free ophthalmic drug formulations. The AriesMD operates in any physical orientation and can be calibrated to dispense a precise dose ranging from 5 µL to 26 µL. A removable eyecup aids in proper positioning of the dispenser to ensure accurate delivery to the eye.  Each dose is individually packaged with a single use dispensing channel to maintain sterility of each delivered dose. An easy to read dose counter informs the patient when it is time to replace the disc cartridge which is a simple process of opening the dispenser, discarding the spent cartridge and dropping in a new cartridge. Operating the AriesMD dispenser is a simple three step process,  index the device, position the device to the eye and press the dispense button – no priming is required. Safety features prevent the device from inadvertent dispense and the compact form factor design makes the AriesMD easy to carry in a purse or a pocket.

Key performance features of our ZEOx1™ and ZEOx2™ ophthalmic drug delivery systems include:

  • Liquid, reconstituted powder to liquid or liquid/liquid recombination dispenser configurations
  • Cartridge reloadable, multi-dose dispenser configurations
  • Compact dispenser footprint for ease of carry in a purse or pocket
  • Unit dose aseptic packaging for preservative free formulations
  • Single use drug dispensing channel maintains sterility of every preservative free dispensed dose

  • Safety lock to prevent inadvertent dispense during handling, storage or transport

  • Mechanically actuated dispense eliminates the need for battery power

  • Sterility assurance throughout the complete preservative free product “in use” cycle

  • Precise dosing that can be calibrated to a specified dose volume between 5 µL to 26 µL
  • Millisecond delivery of the dose to the eye to beat the blink
  • Orientation independent device operation
  • One or two handed operation with adjustable actuation force
  • No device priming required
  • Automatic dose counter
  • Configurable dispense (droplets, stream or spray)
  • Metal free fluid delivery path
  • High efficiency blister packaging reducing drug waste by up to 80%
  • Tamper resistant packaging
  • Intelligent device upgradable

Key performance features of our ZEOx1™ and ZEOx2™ ophthalmic drug delivery systems include:

  • Liquid, reconstituted powder to liquid or liquid/liquid recombination dispenser configurations
  • Cartridge reloadable, multi-dose dispenser configurations
  • Compact dispenser footprint for ease of carry in a purse or pocket
  • Unit dose aseptic packaging for preservative free formulations
  • Single use drug dispensing channel maintains sterility of every preservative free dispensed dose

  • Safety lock to prevent inadvertent dispense during handling, storage or transport

  • Mechanically actuated dispense eliminates the need for battery power

  • Sterility assurance throughout the complete preservative free product “in use” cycle

  • Precise dosing that can be calibrated to a specified dose volume between 5 µL to 26 µL
  • Millisecond delivery of the dose to the eye to beat the blink
  • Orientation independent device operation
  • One or two handed operation with adjustable actuation force
  • No device priming required
  • Automatic dose counter
  • Configurable dispense (droplets, stream or spray)
  • Metal free fluid delivery path
  • High efficiency blister packaging reducing drug waste by up to 80%
  • Tamper resistant packaging
  • Intelligent device upgradable

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