Sublingual Drug Delivery

ZTECH-L™ and ZTECH-P™ sublingual drug delivery systems are designed for non-invasive, systemic delivery of drugs, biopharmaceuticals, biologics or botanicals via the sublingual route. This route of delivery provides convenient dosing for pediatric, geriatric and psychiatric patients with dysphagia.  Sublingual delivery applications include pain management, anaphylaxis, anxiety, depression, hypoglycemia, vitamins, minerals, analgesics, cannabinoids, steroids, proteins and peptides.  Our sublingual delivery systems employ a patient-centric design to facilitate caregiver or self-administration, ease of use and consistent precise delivery.

ZTECH-L™ sublingual drug delivery systems are designed for aqueous or non-aqueous liquid formulations and can be configured to dispense a targeted dose ranging from 20 µL to 200 µL per dose.  ZTECH-P™ sublingual delivery systems can be configured for powder delivery, or to auto-reconstitute a dry powder formulation to a liquid, or auto-combine two separately packaged liquid formulations at the time of dosing by the patient or caregiver.  ZTECH-L™ and ZTECH-P™ sublingual delivery systems are available in mono-dose disposable, mono-dose cartridge reloadable and multi-dose dispenser configurations.

ZTECH-L™ HydraSR™ with calendarized packaging

Key performance features of ZTECH-L™ and ZTECH-P™ sublingual drug delivery systems include:

• Liquid, powder, reconstituted powder to liquid or liquid/liquid recombination dispenser configurations
• Mono-dose disposable and mono-dose reloadable configurations available
• Precise dosing that can be calibrated to a specified delivered dose
• Intuitive design and operation to facilitate first use
• Compact dispenser footprint for ease of carry in a purse or pocket
• Side actuation dispenser device for ease of use

• Mechanically actuated dispense eliminates the need for battery power

• Safety lock to prevent inadvertent dispense during handling, storage or transport

• Intuitive dispenser operation facilitates first time use

• No device priming required
• Dose counter
• Orientation independent device actuation
• Configurable spray plume
• Metal free fluid delivery path
• Non-sterile, terminally sterilized or sterile packaging for preservative free formulations
• Sterility assurance throughout the “in use” product life and in the dispensed dose
• Exceptional primary container barrier properties for long term shelf stability
• Tamper resistant packaging
• Commercially scalable, cost efficient design for manufacturing

Key performance features of ZTECH-L™ and ZTECH-P™ sublingual drug delivery systems include:

• Liquid, powder, reconstituted powder to liquid or liquid/liquid recombination dispenser configurations
• Mono-dose disposable and mono-dose reloadable configurations available
• Precise dosing that can be calibrated to a specified delivered dose
• Intuitive design and operation to facilitate first use
• Compact dispenser footprint for ease of carry in a purse or pocket
• Side actuation dispenser device for ease of use

• Mechanically actuated dispense eliminates the need for battery power

• Safety lock to prevent inadvertent dispense during handling, storage or transport

• Intuitive dispenser operation facilitates first time use

• No device priming required
• Dose counter
• Orientation independent device actuation
• Configurable spray plume
• Metal free fluid delivery path
• Non-sterile, terminally sterilized or sterile packaging for preservative free formulations
• Sterility assurance throughout the “in use” product life and in the dispensed dose
• Exceptional primary container barrier properties for long term shelf stability
• Tamper resistant packaging
• Commercially scalable, cost efficient design for manufacturing